Retinal capillary basement membrane thickness in spiny mice (Acomys cahirinus) with induced and spontaneous diabetes.
نویسندگان
چکیده
Basement membrane thickness was measured in two groups of spiny mice (Acomys cahirinus): one with spontaneous diabetes, the other with streptozotocin-induced diabetes. A statistical analysis of the morphometric results of the two groups showed a significant basement membrane thickening in the group with induced diabetes when compared to the spontaneously diabetic group.
منابع مشابه
The Cairo spiny mouse Acomys cahirinus shows a strong affinity to the Mongolian gerbil Meriones unguiculatus.
The classification of the African spiny mice (genus Acomys) within the Muridae family of rodents has been fraught with controversy. Morphological data suggest a close affinity between this group and true old world mice of the genus Mus. However, the combined results of immunological, biochemical, and DNA melting studies suggest that spiny mice should not even be considered as members of the Mur...
متن کاملEar wound regeneration in the African spiny mouse Acomys cahirinus
While regeneration occurs in a number of taxonomic groups across the Metazoa, there are very few reports of regeneration in mammals, which generally respond to wounding with fibrotic scarring rather than regeneration. A recent report described skin shedding, skin regeneration and extensive ear punch closure in two rodent species, Acomys kempi and Acomys percivali. We examined these striking res...
متن کاملGranulolysis in a Cells of Endocrine Pancreas in Spontaneous and Experimental Diabetes in Animals
By comparison with the B cell of the endocrine pancreas, the A cell has been little studied both in the normal and in pathologic states. Recently, however, several publications have been devoted to A-cell morphology and secretory cycle (1), and to the still controversial distinction between several A-cell types (2). Furthermore, with the availability of the immunoassay procedures for glucagon (...
متن کاملProtective effects of total flavonoids from Flos Puerariae on retinal neuronal damage in diabetic mice
PURPOSE To investigate the potential protective effects of total flavonoids from Flos Puerariae (TFF) on retinal neural cells in diabetic mice. METHODS C57BL/6J mice were intraperitoneally injected with streptozotocin to generate type I diabetes in a murine model, as indicated by blood glucose levels ≥11.1 mmol/l. TFF was administered intragastrically at a dose of 50, 100, or 200 mg/kg/day. A...
متن کاملDifferential osmoregulatory capabilities of common spiny mice (Acomys cahirinus) from adjacent microhabitats
The osmoregulatory function of common spiny mice Acomys cahirinus living on opposite slopes of the lower Nahal Oren (‘Evolution Canyon’) on mount Carmel, Israel, was investigated by increasing the salinity of the water source whilst maintaining a high-protein diet. The southern-facing slope (SFS) of this canyon differs from the northern-facing slope (NFS) as it receives considerably more solar ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- Investigative ophthalmology
دوره 14 7 شماره
صفحات -
تاریخ انتشار 1975